2,7-Diaminobenzopyrylium dyes are live-cell mitochondrial stains

Publication
ACS Bio & Med Chem Au, xx(xx), XX-XXX

Abstract

Small-molecule fluorescent stains enable the imaging of cellular structures without the need for genetic manipulation. Here, we introduce 2,7-diaminobenzopyrylium (DAB) dyes as live-cell mitochondrial stains excited with violet light. This amalgam of the coumarin and rhodamine fluorophore structures yields dyes with high photostability and tunable spectral properties.

Pratik Kumar, PhD
Pratik Kumar, PhD
HHMI Postdoctoral Associate

I am a chemical biologist and I make chemical tools for biology.

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